BOQ - Kitap Yönetim Sistemi
Kitap Bölümü

ULTRA İŞLENMİŞ BESİNLERİN FERTİLİTEYE ETKİSİ

Yüksel SAYIN
Dr., Çankırı Devlet Hastanesi
Gözde EDE İLERİ
Dr. Öğr. Üyesi, Health Sciences
Erişim Durumu
Özel Erişim
Yayınlanma Tarihi
30 June 2026
Sayfa Sayısı
300-313
DOI

Özet

Ultra-processed foods include pre-packaged meals, fast food, sugary drinks, and foods rich in additives. Excessive consumption of these foods can negatively impact both male and female reproductive health. Research shows that ultra-processed foods, due to their high sugar, unhealthy fat, and additive content, can disrupt hormonal balance. This has been linked to ovulation problems, menstrual irregularities, and decreased fertility in women. It is also thought to increase the risk of conditions such as polycystic ovary syndrome (PCOS). In men, heavy consumption of these foods can negatively affect sperm quality. Problems such as decreased sperm count, reduced motility, and DNA damage may occur. These effects largely arise through obesity, insulin resistance, and inflammation. Ultra-processed foods also increase oxidative stress in the body. This can negatively affect the health of both egg and sperm cells, reducing reproductive capacity. In conclusion, excessive consumption of ultra-processed foods can negatively impact fertility. Instead, adopting a diet consisting of more natural, fresh, and balanced foods is important for protecting and improving reproductive health.

Anahtar Kelimeler: ultra işlenmiş besin, fertilite, ovulasyon, doğurganlık çağı

Konu Alanı: Biyoloji -> Biyoloji (diğer) -> Beslenme

Bu Bölüme Atıf Yap
N/A

Ameho, S., & Klutstein, M. (2025). The effect of chronic inflammation on female fertility. Reproduction (Cambridge, England), 169(4), e240197. https://doi.org/10.1530/REP-24-0197.

Baker, P., Slater, S., White, M., Wood, B., Contreras, A., Corvalán, C., Gupta, A., Hofman, K., Kruger, P., Laar, A., Lawrence, M., Mafuyeka, M., Mialon, M., Monteiro, C. A., Nanema, S., Phulkerd, S., Popkin, B. M., Serodio, P., Shats, K., Van Tulleken, C., … Barquera, S. (2025). Towards unified global action on ultra-processed foods: understanding commercial determinants, countering corporate power, and mobilising a public health response. Lancet (London, England), 406(10520), 2703–2726. https://doi.org/10.1016/S0140-6736(25)01567-3.

Bedran, M., Manceau, H., Ollivier, H., Deleschaux, C., Beaufrère, A., M'barek, I. B., & Peoc'h, K. (2026). Pregnancy and Iron: Bridging metabolic demands and supplementation needs. Clinical nutrition ESPEN, 103390. Advance online publication. https://doi.org/10.1016/j.clnesp.2026.103390.

Blaauwendraad, S. M., Dykgraaf, R. H. M., Gaillard, R., Liu, M., Laven, J. S., Jaddoe, V. W. V., & Trasande, L. (2024). Associations of bisphenol and phthalate exposure and anti-Müllerian hormone levels in women of reproductive age. EClinicalMedicine, 74, 102734. https://doi.org/10.1016/j.eclinm.2024.102734.

Busso, D., David, A., Penailillo, R., Echeverría, G., Rigotti, A., Kovalskys, I., Gómez, G., Cortés Sanabria, L. Y., Yépez García, M. C., Pareja, R. G., Herrera-Cuenca, M., Fisberg, M., & On Behalf Of The Elans Study Group (2021). Intake of Vitamin E and C in Women of Reproductive Age: Results from the Latin American Study of Nutrition and Health (ELANS). Nutrients, 13(6), 1954. https://doi.org/10.3390/nu13061954.

Ceretti, E., Bonaccio, M., Iacoviello, L., Di Castelnuovo, A., Ruggiero, E., Donato, F., Lorenzetti, S., Zani, D., & Montano, L. (2024). Consumption of Ultra-Processed Foods and Semen Quality in Healthy Young Men Living in Italy. Nutrients, 16(23), 4129. https://doi.org/10.3390/nu16234129.

Chen, H., Xu, Z., Hu, W., & Li, Y. (2026). Association of allostatic load with female infertility: Findings from national health and nutrition examination survey 2017-2020. African journal of reproductive health, 30(2), 81–90. https://doi.org/10.29063/ajrh2026/v30i2.7.

Cox, C. M., Thoma, M. E., Tchangalova, N., Mburu, G., Bornstein, M. J., Johnson, C. L., & Kiarie, J. (2022). Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis. Human reproduction open, 2022(4), hoac051. https://doi.org/10.1093/hropen/hoac051.

Da Silveira, E. A., Moura, L. A. N. E., Castro, M. C. R., Kac, G., Hadler, M. C. C. M., Noll, P. R. E. S., Noll, M., Rezende, A. T. O., Delpino, F. M., & Oliveira, C. (2022). Prevalence of Vitamin D and Calcium Deficiency and Insufficiency in Women of Childbearing Age and Associated Risk Factors: A Systematic Review and Meta-Analysis. Nutrients, 14(20), 4351. https://doi.org/10.3390/nu14204351.

Devarshi, P. P., Legette, L. L., Grant, R. W., & Mitmesser, S. H. (2021). Total estimated usual nutrient intake and nutrient status biomarkers in women of childbearing age and women of menopausal age. The American journal of clinical nutrition, 113(4), 1042–1052. https://doi.org/10.1093/ajcn/nqaa392.

DiGiorno, A., & Morselli, L. L. (2026). Weight management in women of reproductive age. Obesity and endocrinology, 2(1), wjag007. https://doi.org/10.1093/obendo/wjag007.

Dobranowska, K., Plińska, S., & Dobosz, A. (2024). Dietary and Lifestyle Management of Functional Hypothalamic Amenorrhea: A Comprehensive Review. Nutrients, 16(17), 2967. https://doi.org/10.3390/nu16172967.

Donovan MF, Arbor TC, Bordoni B. Embryology, Yolk Sac. Treasure Island, Florida, USA: StatPearls Publishing, 2025.

Evans, A. T., Alur-Gupta, S., Martinez Steele, E., Meng, Y., Knutson, A. J., & Vitek, W. S. (2025). Consumption of ultra-processed foods and female infertility: a cross-sectional study. Frontiers in public health, 13, 1597910. https://doi.org/10.3389/fpubh.2025.1597910.

FAO. Minimum Dietary Diversity for Women (MDD-W). Rome: Food and Agriculture Organization of the United Nations. 2024. Erişim: https://www.fao.org/nutrition/assessment/tools/minimum-dietary-diversity-women/en/. Erişim tarihi: 01.05.2026.

Fernandes, S., Oliveira, L., Pereira, A., Costa, M. D. C., Raposo, A., Saraiva, A., & Magalhães, B. (2024). Exploring Vitamin B12 Supplementation in the Vegan Population: A Scoping Review of the Evidence. Nutrients, 16(10), 1442. https://doi.org/10.3390/nu16101442.

Gitsi, E., Livadas, S., & Argyrakopoulou, G. (2024). Nutritional and exercise interventions to improve conception in women suffering from obesity and distinct nosological entities. Frontiers in endocrinology, 15, 1426542. https://doi.org/10.3389/fendo.2024.1426542.

Gordon, C. M., Ackerman, K. E., Berga, S. L., Kaplan, J. R., Mastorakos, G., Misra, M., Murad, M. H., Santoro, N. F., & Warren, M. P. (2017). Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism, 102(5), 1413–1439. https://doi.org/10.1210/jc.2017-00131.

Harmon, Q. E., Kissell, K., Jukic, A. M. Z., Kim, K., Sjaarda, L., Perkins, N. J., Umbach, D. M., Schisterman, E. F., Baird, D. D., & Mumford, S. L. (2020). Vitamin D and Reproductive Hormones Across the Menstrual Cycle. Human reproduction (Oxford, England), 35(2), 413–423. https://doi.org/10.1093/humrep/dez283.

Hart, T. L., Petersen, K. S., & Kris-Etherton, P. M. (2022). Nutrition recommendations for a healthy pregnancy and lactation in women with overweight and obesity - strategies for weight loss before and after pregnancy. Fertility and sterility, 118(3), 434–446. https://doi.org/10.1016/j.fertnstert.2022.07.027.

Hoffman, D. J., Reynolds, R. M., & Hardy, D. B. (2017). Developmental origins of health and disease: current knowledge and potential mechanisms. Nutrition reviews, 75(12), 951–970. https://doi.org/10.1093/nutrit/nux053.

Indrio F, Pietrobelli A, Dargenio VN, Marchese F, Grillo A, Vural M, Giardino I, Pettoello-Mantovani M. The key 1000 life-changing days. Glob Pediatr 2023;4:100049.

Islam, M. H., Nayan, M. M., Jubayer, A., & Amin, M. R. (2023). A review of the dietary diversity and micronutrient adequacy among the women of reproductive age in low- and middle-income countries. Food science & nutrition, 12(3), 1367–1379. https://doi.org/10.1002/fsn3.3855.

Jaddoe, V. W., de Jonge, L. L., Hofman, A., Franco, O. H., Steegers, E. A., & Gaillard, R. (2014). First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study. BMJ (Clinical research ed.), 348, g14. https://doi.org/10.1136/bmj.g14.

Kapper, C., Oppelt, P., Ganhör, C., Gyunesh, A. A., Arbeithuber, B., Stelzl, P., & Rezk-Füreder, M. (2024). Minerals and the Menstrual Cycle: Impacts on Ovulation and Endometrial Health. Nutrients, 16(7), 1008. https://doi.org/10.3390/nu16071008.

Lapolla, A., Dalfrà, M. G., Marelli, G., Parrillo, M., Sciacca, L., Sculli, M. A., Succurro, E., Torlone, E., & Vitacolonna, E. (2026). Medical nutrition therapy in physiological pregnancy and in pregnancy complicated by obesity and/or diabetes: SID-AMD recommendations. Acta diabetologica, 63(3), 349–368. https://doi.org/10.1007/s00592-024-02442-7.

Lecorguillé, M., Camier, A., & Kadawathagedara, M. (2022). Weight Changes, Nutritional Intake, Food Contaminants, and Supplements in Women of Childbearing Age, including Pregnant Women: Guidelines for Interventions during the Perinatal Period from the French National College of Midwives. Journal of midwifery & women's health, 67 Suppl 1, S135–S148. https://doi.org/10.1111/jmwh.13423.

Lv, J. L., Wu, Q. J., Wang, X. B., Du, Q., Liu, F. H., Guo, R. H., Leng, X., Pan, B. C., & Zhao, Y. H. (2022). Intake of ultra-processed foods and asthenozoospermia odds: A hospital-based case-control study. Frontiers in nutrition, 9, 941745. https://doi.org/10.3389/fnut.2022.941745.

Miketinas, D., Luo, H., Firth, J. A., Bailey, A., Bender, T., Gross, G., & Brink, L. (2024). Macronutrient and Micronutrient Intake Among US Women Aged 20 to 44 Years. JAMA network open, 7(10), e2438460. https://doi.org/10.1001/jamanetworkopen.2024.38460.

Monteiro, C. A., Cannon, G., Moubarac, J. C., Levy, R. B., Louzada, M. L. C., & Jaime, P. C. (2018). The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing. Public health nutrition, 21(1), 5–17. https://doi.org/10.1017/S1368980017000234.

Monteiro, C. A., Cannon, G., Levy, R. B., Moubarac, J. C., Louzada, M. L., Rauber, F., Khandpur, N., Cediel, G., Neri, D., Martinez-Steele, E., Baraldi, L. G., & Jaime, P. C. (2019). Ultra-processed foods: what they are and how to identify them. Public health nutrition, 22(5), 936–941. https://doi.org/10.1017/S1368980018003762.

Morales-Suarez-Varela, M., & Rocha-Velasco, O. A. (2025). Impact of ultra-processed food consumption during pregnancy on maternal and child health outcomes: A comprehensive narrative review of the past five years. Clinical nutrition ESPEN, 65, 288–304. https://doi.org/10.1016/j.clnesp.2024.12.006.

Mouanness, M., Nava, H., Dagher, C., & Merhi, Z. (2022). Contribution of Advanced Glycation End Products to PCOS Key Elements: A Narrative Review. Nutrients, 14(17), 3578. https://doi.org/10.3390/nu14173578.

Scrinis, G., Popkin, B. M., Corvalan, C., Duran, A. C., Nestle, M., Lawrence, M., Baker, P., Monteiro, C. A., Millett, C., Moubarac, J. C., Jaime, P., & Khandpur, N. (2025). Policies to halt and reverse the rise in ultra-processed food production, marketing, and consumption. Lancet (London, England), 406(10520), 2685–2702. https://doi.org/10.1016/S0140-6736(25)01566-1.

Sherzay, N., Sheikh Abdul Kadir, S. H., & Mohd Nor, N. S. (2026). Impact of maternal micronutrient supplementation on pregnancy outcomes in developing countries: a systematic review and meta-analysis. BMC pregnancy and childbirth, 10.1186/s12884-026-09210-1. Advance online publication. https://doi.org/10.1186/s12884-026-09210-1.

Smit, A. J. P., Hojeij, B., Rousian, M., Schoenmakers, S., Willemsen, S. P., Steegers-Theunissen, R. P. M., & van Rossem, L. (2022). A high periconceptional maternal ultra-processed food consumption impairs embryonic growth: The Rotterdam periconceptional cohort. Clinical nutrition (Edinburgh, Scotland), 41(8), 1667–1675. https://doi.org/10.1016/j.clnu.2022.06.006.

Sultana, A., & Rana, S. (2025). Mechanisms underlying obesity-malignancy connection: a systematic narrative review. Journal of physiology and biochemistry, 81(2), 403–439. https://doi.org/10.1007/s13105-025-01084-9.

Tareke, A. A., Melak, E. G., Mengistu, B. K., Hussen, J., & Molla, A. (2024). Association between maternal dietary diversity during pregnancy and birth outcomes: evidence from a systematic review and meta-analysis. BMC nutrition, 10(1), 151. https://doi.org/10.1186/s40795-024-00960-9.

Touvier, M., da Costa Louzada, M. L., Mozaffarian, D., Baker, P., Juul, F., & Srour, B. (2023). Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait. BMJ (Clinical research ed.), 383, e075294. https://doi.org/10.1136/bmj-2023-075294.

Tristan Asensi, M., Napoletano, A., Sofi, F., & Dinu, M. (2023). Low-Grade Inflammation and Ultra-Processed Foods Consumption: A Review. Nutrients, 15(6), 1546. https://doi.org/10.3390/nu15061546.

Trop-Steinberg, S., Gal, M., Azar, Y., Kilav-Levin, R., & Heifetz, E. M. (2024). Effect of omega-3 supplements or diets on fertility in women: A meta-analysis. Heliyon, 10(8), e29324. https://doi.org/10.1016/j.heliyon.2024.e29324.

Wolfson, J. A., Tucker, A. C., Leung, C. W., Rebholz, C. M., Garcia-Larsen, V., & Martinez-Steele, E. (2025). Trends in Adults' Intake of Un-processed/Minimally Processed, and Ultra-processed foods at Home and Away from Home in the United States from 2003-2018. The Journal of nutrition, 155(1), 280–292. https://doi.org/10.1016/j.tjnut.2024.10.048.

Valle-Hita, C., Salas-Huetos, A., Fernández de la Puente, M., Martínez, M. Á., Canudas, S., Palau-Galindo, A., Mestres, C., Manzanares, J. M., Murphy, M. M., Marquès, M., Salas-Salvadó, J., & Babio, N. (2024). Ultra-processed food consumption and semen quality parameters in the Led-Fertyl study. Human reproduction open, 2024(1), hoae001. https://doi.org/10.1093/hropen/hoae001.

Xue, L., Chen, X., Sun, J., Fan, M., Qian, H., Li, Y., & Wang, L. (2024). Maternal Dietary Carbohydrate and Pregnancy Outcomes: Quality over Quantity. Nutrients, 16(14), 2269. https://doi.org/10.3390/nu16142269.

Ziso, D., Chun, O. K., & Puglisi, M. J. (2022). Increasing Access to Healthy Foods through Improving Food Environment: A Review of Mixed Methods Intervention Studies with Residents of Low-Income Communities. Nutrients, 14(11), 2278. https://doi.org/10.3390/nu14112278.

Zaçe, D., La Gatta, E., Petrella, L., Orfino, A., Viteritti, A. M., & Di Pietro, M. L. (2024). Diet and lifestyles of young women of childbearing age: an Italian survey. Annali dell'Istituto superiore di sanita, 60(2), 89–97. https://doi.org/10.4415/ANN_24_02_02.

Zupo, R., Castellana, F., Boero, G., Matera, E., Colacicco, G., Piscitelli, P., Clodoveo, M. L., Rondanelli, M., Panza, F., Lozupone, M., & Sardone, R. (2024). Processed foods and diet quality in pregnancy may affect child neurodevelopment disorders: a narrative review. Nutritional neuroscience, 27(4), 361–381. https://doi.org/10.1080/1028415X.2023.2197709.

Kitap Bölümü (PDF)
ULTRA İŞLENMİŞ BESİNLERİN FERTİLİTEYE ETKİSİ